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Anti-ENPP3 Antibody (4U880) is an antibody targeting ENPP3. Anti-ENPP3 Antibody (4U880) can be used in ELISA,FC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Anti-ENPP3 Antibody (4U880) is an antibody targeting ENPP3. Anti-ENPP3 Antibody (4U880) can be used in ELISA,FC. |
Alias | RP5-988G15.3, PDNP3, PD-Iβ, PD-IBETA, NPP3, ectonucleotide pyrophosphatase/phosphodiesterase 3, CD203c, B10 |
Ig Type | Human IgG1 |
Clone | 4U880 |
Reactivity | Human, Macaca fascicularis |
Verified Activity | 1. The Binding Activity of Macaca fascicularis ENPP3 with Anti-ENPP3 recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 3.313-4.724 ng/mL. 2. The Binding Activity of Huamn ENPP3 with Anti- ENPP3 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3 at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 2.151-2.492 ng/mL 3. Untransfected HEK293T cells surface (green line) and transfected Human ENPP3 HEK293T stable cells surface (red line) were stained with anti-ENPP3 recombinant antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
Application | ELISA, FC |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP. Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells. Has also alkaline phosphodiesterase activity. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human ENPP3 Protein |
Antigen Species | Human |
Gene ID | 5169 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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