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Synonyms: PTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterogeneous nuclear ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-PTBP1 Antibody (9D226) is an antibody targeting PTBP1. Anti-PTBP1 Antibody (9D226) can be used in ELISA,IHC,WB. |
| Synonyms | PTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterogeneous nuclear ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1 |
| Ig Type | Rabbit IgG |
| Clone | 9D226 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human PTBP1 |
| Antigen Species | Human |
| Gene Name | PTBP1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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