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LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated

TargetMol | SPR
Catalog No. TMPK-00606 Copy Product Info
LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 14.77 kDa and the accession number is AAH26309.1.

LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00606
Copy Product Info
TargetMol | SPR

LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 14.77 kDa and the accession number is AAH26309.1.

LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$1157-10 days7-10 days
10 μg$1887-10 days7-10 days
20 μg$3137-10 days7-10 days
50 μg$6227-10 days7-10 days
100 μg$1,0507-10 days7-10 days
200 μg$1,8807-10 days7-10 days
500 μg$4,2007-10 days7-10 days
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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Biological Activity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 14.77 kDa and the accession number is AAH26309.1.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberAAH26309.1
Synonyms
LIR5,LILRB4,ILT-3,ILT3,HM18,CD85K
Construction
Gln22-Lys123
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
Molecular Weight14.77 kDa (predicted). Due to glycosylation, the protein migrates to 15-20 kDa based on Tris-Bis PAGE result.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage
It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
Research Background
LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

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