Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JPS035, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), specifically HDAC1/2. Its potent activity is associated with an increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1].
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Description | JPS035, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), specifically HDAC1/2. Its potent activity is associated with an increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1]. |
Molecular Weight | 896.15 |
Formula | C49H65N7O7S |
CAS No. | 2669785-84-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JPS035 2669785-84-4 inhibitor inhibit