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Anti-Periostin/OSF-2 Polyclonal Antibody
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Catalog No. TMAB-01371
Alias PN, periostin, osteoblast specific factor, periostin, PDLPOSTN, OSF-2, OSF2
Anti-Periostin/OSF-2 Polyclonal Antibody is a Rabbit antibody targeting Periostin/OSF-2. Anti-Periostin/OSF-2 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
Anti-Periostin/OSF-2 Polyclonal Antibody
Anti-Periostin/OSF-2 Polyclonal Antibody
😃Good
Catalog No. TMAB-01371Alias PN, periostin, osteoblast specific factor, periostin, PDLPOSTN, OSF-2, OSF2
Anti-Periostin/OSF-2 Polyclonal Antibody is a Rabbit antibody targeting Periostin/OSF-2. Anti-Periostin/OSF-2 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Periostin/OSF-2 Polyclonal Antibody is a Rabbit antibody targeting Periostin/OSF-2. Anti-Periostin/OSF-2 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | PN, periostin, osteoblast specific factor, periostin, PDLPOSTN, OSF-2, OSF2 |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma t |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors. |
| Immunogen | KLH conjugated synthetic peptide: human Periostin. |
| Antigen Species | Human |
| Gene Name | POSTN |
| Gene ID | |
| Protein Name | Periostin |
| Uniprot ID | |
| Biology Area | Extracellular matrix,Cell adhesion molecules,Cardiomyocyte precursors,Bone,Focal Adhesions,Other Cell Types |
| Function | Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. |
| Molecular Weight | Theoretical: 100 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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