Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-GABA B Receptor 2 Antibody (1L8)

😃Good
Catalog No. TMAC-01591

Anti-GABA B Receptor 2 Antibody (1L8) is a Mouse antibody targeting GABA B Receptor 2. Anti-GABA B Receptor 2 Antibody (1L8) can be used in WB,IP,IF.

Anti-GABA B Receptor 2 Antibody (1L8)

Anti-GABA B Receptor 2 Antibody (1L8)

😃Good
Catalog No. TMAC-01591
Anti-GABA B Receptor 2 Antibody (1L8) is a Mouse antibody targeting GABA B Receptor 2. Anti-GABA B Receptor 2 Antibody (1L8) can be used in WB,IP,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4267-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-GABA B Receptor 2 Antibody (1L8) is a Mouse antibody targeting GABA B Receptor 2. Anti-GABA B Receptor 2 Antibody (1L8) can be used in WB,IP,IF.
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIn the central nervous system (CNS), γ-aminobutyric acid (GABA) is the maininhibitory neurotransmitter that functions to regulate neuronal firing. GABAexerts its effects through two different kinds of receptors: ionotropic receptors(GABAA R and GABAC R), which produce fast inhibitory signals, and metabotropicreceptors (GABAB R), which produce slow inhibitory signals. TheGABAB R receptor is a heterodimer that consists of two multi-pass membraneproteins, designated GABAB R1 and GABAB R2, both of which belong to theG protein-coupled receptor family and are highly expressed in brain tissue.Together, GABAB R1 and GABAB R2 play a crucial role in the fine-tuning ofinhibitory synaptic transmissions and are implicated in slow wave sleep,muscle relaxation, hippocampal long-term potentiation and antinociceptionevents. Both GABAB R1 and GABAB R2 are regulated by G proteins that havea variety of functions, including activation of potassium channels, inhibitionof adenylyl cyclase (A cyclase) activity and modulation of inositol phospholipidhydrolysis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Amino acids 183-482 mapping within an extracellular domain of GABA(B) R2 of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 130 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-GABA B Receptor 2 Antibody (1L8) | purchase Anti-GABA B Receptor 2 Antibody (1L8) | Anti-GABA B Receptor 2 Antibody (1L8) cost | order Anti-GABA B Receptor 2 Antibody (1L8) | Anti-GABA B Receptor 2 Antibody (1L8) molecular weight