SEMA4B Protein, Human, Recombinant (His)

Catalog No. TMPJ-01349 Copy Product Info

The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.

SEMA4B Protein, Human, Recombinant (His)

Catalog No. TMPJ-01349

Copy Product Info

SEMA4B Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$112	2-4 weeks	2-4 weeks
10 μg	$183	2-4 weeks	2-4 weeks
20 μg	$292	2-4 weeks	2-4 weeks
50 μg	$545	2-4 weeks	2-4 weeks
100 μg	$813	2-4 weeks	2-4 weeks
200 μg	$1,190	2-4 weeks	2-4 weeks
500 μg	$2,070	2-4 weeks	2-4 weeks
1 mg	$2,970	2-4 weeks	2-4 weeks

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	Q9NPR2
Synonyms	Semaphorin-4B,SEMAC and SEMA4B,KIAA1745
Amino Acid	Leu39-Glu712
Construction	Leu39-Glu712
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	86 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.