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Cefpiramide sodium

Name: Cefpiramide sodium
Brand: TargetMol
SKU: T14923
Rating: 4.5 (1 reviews)

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Catalog No. T14923Cas No. 74849-93-7

Alias Wy-44635, SM-1652

Cefpiramide sodium (SM-1652; Wy-44635) is a Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.

Cefpiramide sodium

😃Good

Catalog No. T14923Alias Wy-44635, SM-1652Cas No. 74849-93-7

Cefpiramide sodium (SM-1652; Wy-44635) is a Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
2 mg	$58	5 days	5 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Cefpiramide sodium (SM-1652; Wy-44635) is a Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
In vitro	Cefpiramide was moderately susceptible to hydrolysis by a variety of beta-lactamases from Gram-negative bacilli. Cefpiramide inhibited non-enterococcal streptococci, methicillin-susceptible staphylococci, Neisseria gonorrhoeae, N. meningitidis, and beta-lactamase-negative Haemophilus influenzae [1].
In vivo	Cefpiramide inhibited staphylococci and streptococci and had appreciable activity against Streptococcus faecalis and Listeria moncytogenes [3]. Pharmacokinetic studies in mice showed that cefpiramide attained a peak serum concentration of 12 micrograms/ml and a serum half-life of 40 min, which are higher than attained by cefoperazone with values of 4 micrograms/ml and 18 min. These factors may have caused the combined cefpiramide-gentamicin therapy to result in significantly improved survival rates in mice as well as in higher bactericidal titers than the cefoperazone-gentamicin combination [2].
Synonyms	Wy-44635, SM-1652

Chemical Properties

Molecular Weight	635.63
Formula	C₂₅H₂₄N₈NaO₇S₂
Cas No.	74849-93-7
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 39 mg/mL (61.36 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (3.15 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5732 mL	7.8662 mL	15.7324 mL	78.6621 mL
5 mM	0.3146 mL	1.5732 mL	3.1465 mL	15.7324 mL
10 mM	0.1573 mL	0.7866 mL	1.5732 mL	7.8662 mL
20 mM	0.0787 mL	0.3933 mL	0.7866 mL	3.9331 mL
50 mM	0.0315 mL	0.1573 mL	0.3146 mL	1.5732 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc