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Thioproperazine
🥰Excellent
Catalog No. T21368Cas No. 316-81-4
Alias SKF 5883, RP 7843, Megeptil, Mazeptyl, Majeptyl, Cephalmin
Thioproperazine (RP 7843) is an orally effective antipsychotic also used as a tranquilizer and antiemetic for the treatment of schizophrenia and the manic phase of bipolar disorder, acting as a histamine and adrenergic receptor blocker.
Thioproperazine
🥰Excellent
Purity: 99.45%
Catalog No. T21368Alias SKF 5883, RP 7843, Megeptil, Mazeptyl, Majeptyl, CephalminCas No. 316-81-4
Thioproperazine (RP 7843) is an orally effective antipsychotic also used as a tranquilizer and antiemetic for the treatment of schizophrenia and the manic phase of bipolar disorder, acting as a histamine and adrenergic receptor blocker.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $31 | In Stock | |
| 5 mg | $71 | In Stock | |
| 10 mg | $113 | In Stock | |
| 25 mg | $189 | In Stock | |
| 50 mg | $283 | In Stock | |
| 100 mg | $419 | In Stock |
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Purity:99.45%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Thioproperazine (RP 7843) is an orally effective antipsychotic also used as a tranquilizer and antiemetic for the treatment of schizophrenia and the manic phase of bipolar disorder, acting as a histamine and adrenergic receptor blocker. |
| In vitro | Thioproperazine (5 mg/kg) pretreatment in rats significantly increased ³H-dopamine synthesis and release in striatal slices (by 88% and 49%, respectively)[1]. |
| Synonyms | SKF 5883, RP 7843, Megeptil, Mazeptyl, Majeptyl, Cephalmin |
| Molecular Weight | 446.63 |
| Formula | C22H30N4O2S2 |
| Cas No. | 316-81-4 |
| Smiles | O=S(=O)(C1=CC=C2SC=3C=CC=CC3N(C2=C1)CCCN4CCN(C)CC4)N(C)C |
| Relative Density. | 1.1476 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | H2O: < 1 mg/mL (insoluble) DMSO: 10 mg/mL (22.39 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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