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Isosinensetin

🥰Excellent
Catalog No. T2S0223Cas No. 17290-70-9
Alias 6-Demethoxynobiletin

1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.

Isosinensetin

Isosinensetin

🥰Excellent
Purity: 99.05%
Catalog No. T2S0223Alias 6-DemethoxynobiletinCas No. 17290-70-9
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$60In StockIn Stock
5 mg$145In StockIn Stock
10 mg$217In StockIn Stock
25 mg$363In StockIn Stock
50 mg$539In StockIn Stock
100 mg$778In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.05%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.
Synonyms6-Demethoxynobiletin
Chemical Properties
Molecular Weight372.37
FormulaC20H20O7
Cas No.17290-70-9
SmilesCOc1ccc(cc1OC)-c1cc(=O)c2c(OC)cc(OC)c(OC)c2o1
Relative Density.1.244 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 3.72 mg/mL (10 mM), Sonication is recommended.
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6855 mL13.4275 mL26.8550 mL134.2750 mL
5 mM0.5371 mL2.6855 mL5.3710 mL26.8550 mL
10 mM0.2686 mL1.3428 mL2.6855 mL13.4275 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

P-gp (P-glycoprotein)P-gpPgpP-glycoproteinMultidrug resistance protein 1MDR1IsosinensetinInhibitorinhibitHIVProteaseHIV-1HIV ProteaseCluster of differentiation 243CD243BacterialAntioxidantABCB1
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