PEG4-aminooxy-MMAF

Name: PEG4-aminooxy-MMAF
Brand: TargetMol
SKU: T18534
Rating: 4.5 (1 reviews)

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Catalog No. T18534Cas No. 1415246-35-3

PEG4-aminooxy-MMAF is a drug-linker conjugate designed for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. It incorporates MMAF, a powerful antitubulin agent, connected through a non-cleavable PEG4 linker[1].

PEG4-aminooxy-MMAF

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Catalog No. T18534Cas No. 1415246-35-3

Pack Size	Price	Availability	Quantity
100 mg	Inquiry	Backorder
500 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	923.19
Formula	C₄₇H₈₂N₆O₁₂
Cas No.	1415246-35-3
Relative Density.	1.132 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (108.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0832 mL	5.4160 mL	10.8320 mL	54.1600 mL
5 mM	0.2166 mL	1.0832 mL	2.1664 mL	10.8320 mL
10 mM	0.1083 mL	0.5416 mL	1.0832 mL	5.4160 mL
20 mM	0.0542 mL	0.2708 mL	0.5416 mL	2.7080 mL
50 mM	0.0217 mL	0.1083 mL	0.2166 mL	1.0832 mL
100 mM	0.0108 mL	0.0542 mL	0.1083 mL	0.5416 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc