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Isoflupredone

Name: Isoflupredone
Brand: TargetMol
SKU: T41303
Price: 57 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T41303Cas No. 338-95-4

Alias Isoflupredonum, Isoflupredona, Delta-Fluorocortisone, 9-Fluoroprednisolone

Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expression of inflammatory mediators. Isoflupredone has anti-inflammatory and immunosuppressive effects and can be used to treat a variety of musculoskeletal, allergic and systemic inflammatory diseases.

Isoflupredone

🥰Excellent

Purity: 99.85%

Catalog No. T41303Alias Isoflupredonum, Isoflupredona, Delta-Fluorocortisone, 9-FluoroprednisoloneCas No. 338-95-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$57	In Stock	In Stock
2 mg	$83	In Stock	In Stock
5 mg	$139	In Stock	In Stock
10 mg	$247	In Stock	In Stock
25 mg	$538	In Stock	In Stock
50 mg	$778	-	In Stock
100 mg	$1,090	-	In Stock
1 mL x 10 mM (in DMSO)	$153	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.85%

ee:100%

Resource Download

COA CSFC FNMR HNMR LCMS

Product Introduction

Bioactivity

Description	Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expression of inflammatory mediators. Isoflupredone has anti-inflammatory and immunosuppressive effects and can be used to treat a variety of musculoskeletal, allergic and systemic inflammatory diseases.
In vivo	Isoflupredone effectively reduces serum potassium levels in horses and serves as a potent medication for managing recurrent airway obstruction in these animals [1].
Synonyms	Isoflupredonum, Isoflupredona, Delta-Fluorocortisone, 9-Fluoroprednisolone

Chemical Properties

Molecular Weight	378.43
Formula	C₂₁H₂₇FO₅
Cas No.	338-95-4
Smiles	[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 12 mg/mL (31.71 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.28 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6425 mL	13.2125 mL	26.4250 mL	132.1248 mL
5 mM	0.5285 mL	2.6425 mL	5.2850 mL	26.4250 mL
10 mM	0.2642 mL	1.3212 mL	2.6425 mL	13.2125 mL
20 mM	0.1321 mL	0.6606 mL	1.3212 mL	6.6062 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Δ-FluorocortisoneIsoflupredone