Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2-Methylthio-AMP diTEA (2-MeSAMP) is a selective and direct antagonist of the P2Y12 receptor, effectively inhibiting ADP-dependent platelet aggregation[1][2][3].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | 2-Methylthio-AMP diTEA (2-MeSAMP) is a selective and direct antagonist of the P2Y12 receptor, effectively inhibiting ADP-dependent platelet aggregation[1][2][3]. |
In vitro | 2-Methylthio-AMP (2-MeSAMP) diTEA inhibits agonist-mediated αIIbβ3 activation in platelets[1]. 2-methylthio-AMP (50 μM; for 5 minutes) diTEA does not significantly inhibit thrombin, PAR1-AP, PAR4-AP, or ADP-mediated platelet Ca2+ mobilization. 2-methylthio-AMP diTEA fails to inhibit Ca2+ mobilization in P2Y12-deficient mouse platelets and does not raise cAMP or induce vasodilator-stimulated phosphoprotein phosphorylation in wild-type platelets[1]. |
Molecular Weight | 595.69 |
Formula | C23H46N7O7PS |
CAS No. | 1227193-98-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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2-Methylthio-AMP diTEA 1227193-98-7 2MethylthioAMP diTEA 2 Methylthio AMP diTEA inhibitor inhibit