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Anti-Ephrin A1/EFNA1 Antibody (3F76) is a Rabbit antibody targeting Ephrin A1/EFNA1. Anti-Ephrin A1/EFNA1 Antibody (3F76) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-Ephrin A1/EFNA1 Antibody (3F76) is a Rabbit antibody targeting Ephrin A1/EFNA1. Anti-Ephrin A1/EFNA1 Antibody (3F76) can be used in IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 3F76 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human EFNA1 in human pancreas with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ephrin-A1 / EFNA1 (rh Ephrin-A1 / EFNA1; TMPY-01210; NP_004419.2; Met1-Ser182). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Ephrin-A1 / EFNA1 protein (TMPY-01210) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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