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N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $39 | 5 days | |
5 mg | $60 | Backorder |
Description | N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. |
In vitro | PROTACs consist of two ligands linked together: one ligand binds an E3 ubiquitin ligase, and the other targets a specific protein. These compounds harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | n-propargyl-peg4-carbonyl-n-bis-peg1-methyl-ester |
Molecular Weight | 519.58 |
Formula | C24H41NO11 |
Cas No. | 2112732-01-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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