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STAT1 Protein, Human, Recombinant
(Synonyms: Transcription Factor ISGF-3 Components p91/p84, STAT1, Signal Transducer and Activator of Transcription 1-α/β, Signal Transducer and Activator of Transcription 1-α/Beta, Signal Transducer and Activator of Transcription 1-Alpha/Beta) Copy Product InfoSynonyms: Transcription Factor ISGF-3 Components p91/p84, STAT1, Signal Transducer and Activator of Transcription 1-α/β, Signal Transducer and Activator of Transcription 1-α/Beta, Signal Transducer and Activator of Transcription 1-Alpha/Beta
Catalog No. TMPJ-00961 Copy Product Info
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $80 | - | In Stock | |
| 10 μg | $129 | - | In Stock | |
| 20 μg | $198 | - | In Stock | |
| 50 μg | $390 | - | In Stock | |
| 100 μg | $642 | - | In Stock | |
| 200 μg | $1,060 | 7-10 days | 7-10 days | |
| 500 μg | $2,070 | 7-10 days | 7-10 days | |
| 1 mg | $2,970 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:82%
Appearance:Lyophilized powder
Color:White
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Product Introduction
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| Description | Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P42224 |
| Amino Acid | Met1-Val712 |
| Construction | Met1-Val712 |
| Protein Purity | Greater than 68% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 0.02% Tween 80, 5% Sucrose, 4% Mannitol, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Transcription Factor ISGF-3 Components p91/p84, STAT1, Signal Transducer and Activator of Transcription 1-α/β, Signal Transducer and Activator of Transcription 1-α/Beta, Signal Transducer and Activator of Transcription 1-Alpha/Beta |
| Research Background |
| Molecular Weight | 85 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: STAT1 Protein, Human, Recombinant chemical structure | STAT1 Protein, Human, Recombinant molecular weight
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