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Cryptating agent 222

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Catalog No. T20736Cas No. 23978-09-8
Alias NSC-264495, NSC264495, NSC 264495, Cryptate 222

Cryptating agent 222 (NSC-264495) is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion and forms ligands with metal cations.

Cryptating agent 222

Cryptating agent 222

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Purity: 99.91%
Catalog No. T20736Alias NSC-264495, NSC264495, NSC 264495, Cryptate 222Cas No. 23978-09-8
Cryptating agent 222 (NSC-264495) is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion and forms ligands with metal cations.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$40-In Stock
1 mL x 10 mM (in DMSO)$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.91%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Cryptating agent 222 (NSC-264495) is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion and forms ligands with metal cations.
SynonymsNSC-264495, NSC264495, NSC 264495, Cryptate 222
Chemical Properties
Molecular Weight376.49
FormulaC18H36N2O6
Cas No.23978-09-8
SmilesC1COCCN2CCOCCOCCN(CCO1)CCOCCOCC2
Relative Density.1.11 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 100 mg/mL (265.61 mM), Sonication is recommended.
DMSO: 3.77 mg/mL (10.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.6561 mL13.2806 mL26.5611 mL132.8057 mL
5 mM0.5312 mL2.6561 mL5.3122 mL26.5611 mL
10 mM0.2656 mL1.3281 mL2.6561 mL13.2806 mL
H2O
1mg5mg10mg50mg
20 mM0.1328 mL0.6640 mL1.3281 mL6.6403 mL
50 mM0.0531 mL0.2656 mL0.5312 mL2.6561 mL
100 mM0.0266 mL0.1328 mL0.2656 mL1.3281 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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