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Anti-GJA1 Antibody (6Q512) is a Rabbit antibody targeting GJA1. Anti-GJA1 Antibody (6Q512) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-GJA1 Antibody (6Q512) is a Rabbit antibody targeting GJA1. Anti-GJA1 Antibody (6Q512) can be used in IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 6Q512 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human GJA1 in mouse heart with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human GJA1 in cynomolgus heart with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human GJA1. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | GJA1 encodes connexin 43 (Cx43), the most widely expressed gap junction protein. The de novo missense mutations in GJA1 (gap junction protein alpha 1) cause EKVP. Erythrokeratodermia variabilis et progressiva (EKVP) is a rare, inherited skin disease that is characterized by transient figurate patches of erythema, localized or generalized scaling, and frequent palmoplantar keratoderma. GJA1 and SERPINE2 represent potential gene markers associated with oocyte maturation. In the GJA1 gene which encodes gap junction channel protein connexin 43. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide corresponding to the center region of the Human GJA1 |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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