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Synonyms: Transforming Growth Factor β-1, Transforming Growth Factor Beta-1, TGF-β-1, TGF-β1, TGF-Beta-1, TGFB1, TGFB, Latency-Associated Peptide, LAP

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $198 | - | In Stock | |
| 10 μg | $345 | 7-10 days | 7-10 days | |
| 20 μg | $579 | - | In Stock | |
| 50 μg | $987 | 7-10 days | 7-10 days | |
| 100 μg | $1,600 | 7-10 days | 7-10 days |
| Description | Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-Avi |
| Accession Number | P01137 |
| Amino Acid | Ala279-Ser390 |
| Construction | Ala279-Ser390 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) https://cdn.targetmol.com/group3/M00/12/EA/CgoaEGZG0ymEGSSuAAAAAAK9bTg468.png |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Glycine-HCl, 150 mM NaCl, pH2.5. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Transforming Growth Factor β-1, Transforming Growth Factor Beta-1, TGF-β-1, TGF-β1, TGF-Beta-1, TGFB1, TGFB, Latency-Associated Peptide, LAP |
| Research Background |
| Molecular Weight | 12-18 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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