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TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

(Synonyms: Transforming Growth Factor β-1, Transforming Growth Factor Beta-1, TGF-β-1, TGF-β1, TGF-Beta-1, TGFB1, TGFB, Latency-Associated Peptide, LAP) Copy Product Info

Synonyms: Transforming Growth Factor β-1, Transforming Growth Factor Beta-1, TGF-β-1, TGF-β1, TGF-Beta-1, TGFB1, TGFB, Latency-Associated Peptide, LAP

Catalog No. TMPJ-00249 Copy Product Info
Purity: 98.6%
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

Batch Information

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Purity:98.6%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
Species
Human
Expression System
HEK293 Cells
TagN-Avi
Accession NumberP01137
Amino AcidAla279-Ser390
ConstructionAla279-Ser390
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
https://cdn.targetmol.com/group3/M00/12/EA/CgoaEGZG0ymEGSSuAAAAAAK9bTg468.png
Endotoxin< 10 EU/mg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Glycine-HCl, 150 mM NaCl, pH2.5.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsTransforming Growth Factor β-1, Transforming Growth Factor Beta-1, TGF-β-1, TGF-β1, TGF-Beta-1, TGFB1, TGFB, Latency-Associated Peptide, LAP
Research Background
Chemical Properties
Molecular Weight12-18 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated chemical structure | TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated molecular weight