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Anti-HEG1 Polyclonal Antibody (Synonyms: MSTP112, MST112, KIAA1237, HEG1, HEG homolog 1, HEG)
Catalog No. TMAB-00843 Copy Product Info
🥰Excellent
Anti-HEG1 Polyclonal Antibody is a Rabbit antibody targeting HEG1. Anti-HEG1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-HEG1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00843
Synonyms MSTP112, MST112, KIAA1237, HEG1, HEG homolog 1, HEG
Anti-HEG1 Polyclonal Antibody is a Rabbit antibody targeting HEG1. Anti-HEG1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-HEG1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HEG1 Polyclonal Antibody is a Rabbit antibody targeting HEG1. Anti-HEG1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | MSTP112, MST112, KIAA1237, HEG1, HEG homolog 1, HEG |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (HEG homolog 1) Polyclonal Antibody, Unconjugated (TMAB-00843) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 min and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (HEG homolog 1) Polyclonal Antibody, Unconjugated (TMAB-00843) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 90 minutes, and DAPI for nucleus staining.   |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Cell junction.Isoform 2: Secreted (Potential). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | HEG1 (HEG homolog 1) is also known as HEG and is a 1,381 amino acid protein that exists as two alternatively spliced isoforms, one of which is a single-pass membrane protein and the other of which is secreted. HEG1, which is expressed in endothelial cells and smooth muscle cells of heart tissue, contains two EGF-like domains that play a role in calcium-binding events which may regulate concentric heart growth. The gene encoding HEG1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Immunogen | KLH conjugated synthetic peptide: human HEG1 |
| Antigen Species | Human |
| Gene Name | HEG1 |
| Gene ID | |
| Protein Name | Protein HEG homolog 1 |
| Uniprot ID | |
| Biology Area | Growth Factors,Transcription factors/regulators,Angiogenesis and vasculogenesis,Tight Junctions,Calcium Binding Proteins |
| Function | Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity May act through the stabilization of endothelial cell junctions. |
| Molecular Weight | Theoretical: 144 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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