AKR1C4 Protein, Human, Recombinant (His)

Catalog No. TMPY-00481 Copy Product Info

AKR1C4 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P17516.

AKR1C4 Protein, Human, Recombinant (His)

Catalog No. TMPY-00481

Copy Product Info

AKR1C4 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P17516.

Pack Size	Price	USA Stock	Global Stock
5 μg	$108	7-10 days	7-10 days
10 μg	$178	7-10 days	7-10 days
20 μg	$296	7-10 days	7-10 days
50 μg	$696	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
Description	AKR1C4 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P17516.
Species	Human
Expression System	E. coli
Tag	N-6His
Accession Number	P17516
Synonyms	HAKRA,DD-4,DD4,CHDR,CDR,C11,aldo-keto reductase family 1, member C4,AKR1C4,3-α-HSD,3-alpha-HSD
Construction	Met1-Tyr323
Protein Purity	> 90% as determined by SDS-PAGE.
Molecular Weight	39.3 kDa (Predicted); 35-40 kDa (Reducing conditions)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Solutions are shipped with dry ice.
Research Background	Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.