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Optovin

Name: Optovin
Brand: TargetMol
SKU: T6617
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T6617Cas No. 348575-88-2

Optovin is a TRPA1 activator, which is reversibly photoactivated.

Optovin

🥰Excellent

Purity: 99.67%

Catalog No. T6617Cas No. 348575-88-2

Optovin is a TRPA1 activator, which is reversibly photoactivated.

Pack Size	Price	Availability
2 mg	$33	In Stock
5 mg	$52	In Stock
10 mg	$85	In Stock
25 mg	$163	In Stock
50 mg	$263	In Stock
100 mg	$428	In Stock
200 mg	$623	In Stock
1 mL x 10 mM (in DMSO)	$58	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.67%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Optovin is a TRPA1 activator, which is reversibly photoactivated.
Targets&IC50	TRPA1:2 μM(EC50)
In vitro	Optovin activates human TRPA1 via structure dependent photochemical reactions. [1]
In vivo	Optovin enables real-time optical control of neurons, and also elicits nociceptive behaviors in adult mice. In animals with severed spinal cords, optovin treatment enables control of motor activity in the paralyzed extremities by localized illumination. [1]

Chemical Properties

Molecular Weight	315.41
Formula	C₁₅H₁₃N₃OS₂
Cas No.	348575-88-2
Smiles	Cc1cc(\C=C2/SC(=S)NC2=O)c(C)n1-c1cccnc1
Relative Density.	1.38 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 59 mg/mL (187.06 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.34 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1705 mL	15.8524 mL	31.7048 mL	158.5238 mL
5 mM	0.6341 mL	3.1705 mL	6.3410 mL	31.7048 mL
10 mM	0.3170 mL	1.5852 mL	3.1705 mL	15.8524 mL
20 mM	0.1585 mL	0.7926 mL	1.5852 mL	7.9262 mL
50 mM	0.0634 mL	0.3170 mL	0.6341 mL	3.1705 mL
100 mM	0.0317 mL	0.1585 mL	0.3170 mL	1.5852 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc