Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

YAP-TEAD-IN-1 acetate

🥰Excellent
Catalog No. TP2160L1
Alias YAP-TEAD-IN-1 acetate (1659305-78-8 Free base)

YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.

YAP-TEAD-IN-1 acetate
Other Forms of YAP-TEAD-IN-1 acetate:
YAP-TEAD-IN-1TP21601659305-78-8
Backorder
View details

YAP-TEAD-IN-1 acetate

🥰Excellent
Purity: 99.57%
Catalog No. TP2160L1Alias YAP-TEAD-IN-1 acetate (1659305-78-8 Free base)
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$147-In Stock
5 mg$347-In Stock
10 mg$580-In Stock
25 mg$928-In Stock
50 mg$1,260-In Stock
100 mg$1,690-In Stock
500 mg$3,420-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.57%
Contact us for more batch information

Resource Download

COA HPLC MS

Product Introduction

Bioactivity
Description
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.
In vitro
YAP-TEAD-IN-1 acetate (2 μM) shows a higher binding affinity to TEAD1 (Kd = 15 nM) than YAP (50-171) (Kd = 40 nM)[1].
SynonymsYAP-TEAD-IN-1 acetate (1659305-78-8 Free base)
Chemical Properties
Molecular Weight2079.92
FormulaC95H148ClN23O23S2
SmilesO=C(N(CCC1)[C@@H]1C(N[C@@H](C(N)=O)CCC(O)=O)=O)[C@H](CCC2)N2C([C@H](CCCCN)NC([C@H](CSSCC[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H]3CCCCN)=O)CCCNC(N)=N)=O)CC(C)C)=O)NC([C@H](CC4=CC(Cl)=CC=C4)NC([C@H](CCC5)N5C([C@H](C(C)C)NC(C)=O)=O)=O)=O)NC([C@@H](NC([C@@](NC([C@@H](NC([C@@](CCC6)([H])N6C([C@](NC3=O)([H])CCCC)=O)=O)C)=O)([H])CO)=O)CC7=CC=CC=C7)=O)=O)=O.CC(O)=O
Relative Density.no data available
SequenceAc-Val-Pro-Phe(3-Cl)-Hcy(1)-Leu-Arg-Lys-Nle-Pro-Ala-Ser-Phe-Cys(1)-Lys-Pro-Pro-Glu
Sequence ShortVPXXLRKXPASFCKPPE
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (48.08 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.4808 mL2.4039 mL4.8079 mL24.0394 mL
5 mM0.0962 mL0.4808 mL0.9616 mL4.8079 mL
10 mM0.0481 mL0.2404 mL0.4808 mL2.4039 mL
20 mM0.0240 mL0.1202 mL0.2404 mL1.2020 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

YAP-TEAD-IN-1 AcetateYAPTEADIN1 acetateYAP–TEADYAP TEAD IN 1 acetate1659305-78-8 Free base1659305-78-8
Related Tags: buy YAP-TEAD-IN-1 acetate | purchase YAP-TEAD-IN-1 acetate | YAP-TEAD-IN-1 acetate cost | order YAP-TEAD-IN-1 acetate | YAP-TEAD-IN-1 acetate chemical structure | YAP-TEAD-IN-1 acetate in vitro | YAP-TEAD-IN-1 acetate formula | YAP-TEAD-IN-1 acetate molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.