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Anti-SEMA4D Antibody-PE (1D998) is a PE-conjugated Rabbit antibody targeting SEMA4D. Anti-SEMA4D Antibody-PE (1D998) can be used in FCM.
Description | Anti-SEMA4D Antibody-PE (1D998) is a PE-conjugated Rabbit antibody targeting SEMA4D. Anti-SEMA4D Antibody-PE (1D998) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1D998 |
Reactivity | Mouse |
Verified Activity | Flow cytometric analysis of mouse SEMA4D (CD100) expression on splenocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Semaphorin 4D / SEMA4D / CD100 (rM Semaphorin 4D / SEMA4D / CD100; TMPY-01836; NP_038688.2; Met1-Arg733) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties. |
Conjucates | PE |
Others Formats | Unconjugated/APC/FITC |
Antibody Types Available | 4 |
Immunogen | Recombinant Mouse Semaphorin 4D / SEMA4D / CD100 protein (TMPY-01836) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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