IL-21 Protein, Rat, Recombinant

Name: IL-21 Protein, Rat, Recombinant
Brand: TargetMol
SKU: TMPY-05468
Rating: 4.5 (1 reviews)

(Synonyms: IL-21, Il21) Copy Product Info

Synonyms: IL-21, Il21

Catalog No. TMPY-05468 Copy Product Info

IL-21 Protein, Rat, Recombinant is expressed in E. coli. The accession number is A3QPB9.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	7-10 days	7-10 days
10 µg	$167	7-10 days	7-10 days
20 µg	$275	7-10 days	7-10 days
50 µg	$498	7-10 days	7-10 days
100 µg	$896	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	IL-21 Protein, Rat, Recombinant is expressed in E. coli. The accession number is A3QPB9.
Species	Rat
Expression System	E. coli
Tag	Tag Free
Accession Number	A3QPB9
Construction	A DNA sequence encoding the rat IL21 (NP_001102413.1) (Pro25-Ser146) was expressed with an initial Met.
Protein Purity	> 95% as determined by SDS-PAGE.
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	IL-21, Il21
Research Background	IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Chemical Properties

Molecular Weight	14.5 kDa (predicted)
Relative Density.	no data available

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.