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Anti-COX-2 Polyclonal Antibody 2

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Catalog No. TMAB-00470

Anti-COX-2 Polyclonal Antibody 2 is a Rabbit antibody targeting COX-2. Anti-COX-2 Polyclonal Antibody 2 can be used in ICC/IF,FCM.

Anti-COX-2 Polyclonal Antibody 2

Anti-COX-2 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-00470
Anti-COX-2 Polyclonal Antibody 2 is a Rabbit antibody targeting COX-2. Anti-COX-2 Polyclonal Antibody 2 can be used in ICC/IF,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$220 7-10 days
100 μL$372 7-10 days
200 μL$528 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Polyclonal

Application: ICC/IF,FCM

Reactivity: Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
4% Paraformaldehyde-fixed Hela (H) cell; Triton X-100 at RT for 20 min; Antibody incubation with (Cyclooxygenase 2) polyclonal Antibody, unconjugated (TMAB-00470) 1:100, 90 min at 37°C; followed by conjugated Goat Anti-Rabbit IgG antibody (green ) at 37°C for 90 min, DAPI (blue) was used to stain the cell nucleus. PBS instead of the primary antibody was used as the blank control.
Application
ICC/IF,FCM
Recommended Dose
ICC/IF: 1:50-200; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMicrosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Post-translational modifications : S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundProstaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Cyclooxygenase 2
Antigen Species
Human
Gene ID
5743
Uniprot ID
Biology Area
Hormone biosynthesis,Tumor biomarkers,Lipoprotein metabolism,Platelets,Cholesterol Metabolism,Macrophage / Inflamm.,Hormone biosynthesis,Cholesterol Metabolism,Lipoprotein metabolism,Heart disease,Prostaglandins
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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