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Anti-PDGF-BB Polyclonal Antibody
(Synonyms: PDGF-BB, PDGFBB) Copy Product Info
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Synonyms: PDGF-BB, PDGFBB
Catalog No. TMAB-01352 Copy Product Info
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Anti-PDGF-BB Polyclonal Antibody is a Rabbit antibody targeting PDGF-BB. Anti-PDGF-BB Polyclonal Antibody can be used in FCM,IF,IHC-Fr,WB.
Anti-PDGF-BB Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-PDGF-BB Polyclonal Antibody is a Rabbit antibody targeting PDGF-BB. Anti-PDGF-BB Polyclonal Antibody can be used in FCM,IF,IHC-Fr,WB. |
| Synonyms | PDGF-BB, PDGFBB |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Note=Released by platelets upon wounding. |
| Tissue Specificity | Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family. |
| Immunogen | KLH conjugated synthetic peptide: human PDGF-B |
| Antigen Species | Human |
| Gene Name | PDGFB |
| Gene ID | |
| Protein Name | Platelet-derived growth factor subunit B |
| Uniprot ID | |
| Biology Area | Response to hypoxia,PDGF,Inflammatory mediators,Serum Proteins,Angiogenesis and vasculogenesis,Hypoxia,Heart disease,PDGF |
| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. |
| Molecular Weight | Theoretical: 27 kDa. Actual: 27 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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