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Prostaglandin F2α 1,15-lactone
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Catalog No. T37327Cas No. 55314-49-3
Alias Prostaglandin F2α 1,15-lactone
PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective.
Prostaglandin F2α 1,15-lactone
😃Good
Catalog No. T37327Alias Prostaglandin F2α 1,15-lactoneCas No. 55314-49-3
PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $316 | 35 days | |
| 5 mg | $1,390 | 35 days | |
| 10 mg | $2,460 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective. |
| Synonyms | Prostaglandin F2α 1,15-lactone |
| Molecular Weight | 336.47 |
| Formula | C20H32O4 |
| Cas No. | 55314-49-3 |
| Relative Density. | 1.051 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | Ethanol:PBS (30:70): 8 mg/mL (23.78 mM), Sonication is recommended. PBS (pH 7.2): <50 ug/mL, Sonication is recommended. DMF: >20.4 mg/mL, Sonication is recommended. Ethanol: >105 mg/mL, Sonication is recommended. DMSO: >10 mg/mL, Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
Ethanol:PBS (30:70)
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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