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Anti-Phospho-Tau (Thr217) Antibody (1W171)
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Catalog No. TMAY-01632
Alias Tau-PHF6, tau-40, TAU, PPP1R103, PPND, MTBT2, MTBT1, MSTD, MGC138549, MAPTL, FTDP-17, FLJ31424, DDPAC
Anti-Phospho-Tau (Thr217) Antibody (1W171) is a Rabbit antibody targeting Phospho-Tau (Thr217). Anti-Phospho-Tau (Thr217) Antibody (1W171) can be used in WB.
Anti-Phospho-Tau (Thr217) Antibody (1W171)
Anti-Phospho-Tau (Thr217) Antibody (1W171)
😃Good
Catalog No. TMAY-01632Alias Tau-PHF6, tau-40, TAU, PPP1R103, PPND, MTBT2, MTBT1, MSTD, MGC138549, MAPTL, FTDP-17, FLJ31424, DDPAC
Anti-Phospho-Tau (Thr217) Antibody (1W171) is a Rabbit antibody targeting Phospho-Tau (Thr217). Anti-Phospho-Tau (Thr217) Antibody (1W171) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $80 | 7-10 days | |
| 100 μL | $233 | 7-10 days |
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Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Tau (Thr217) Antibody (1W171) is a Rabbit antibody targeting Phospho-Tau (Thr217). Anti-Phospho-Tau (Thr217) Antibody (1W171) can be used in WB. |
| Alias | Tau-PHF6, tau-40, TAU, PPP1R103, PPND, MTBT2, MTBT1, MSTD, MGC138549, MAPTL, FTDP-17, FLJ31424, DDPAC |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1W171 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extracts from mouse brain, untreated (line A); treated with λ-phosphatase (line B) using Phospho-Tau (Thr217) rabbit monoclonal Antibody at 1:2000 dilution. (Validation Experiment) 2. Western blot analysis of extracts from Hela using Phospho-Tau (Thr217) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment) 3. Western blot analysis of extracts from Rat brain using Phospho-Tau (Thr217) rabbit monoclonal Antibody at 1:10000 dilution. 4. Western blot analysis of 200 ng Recombinant Human Tau Protein (Full Length) (line A) and 200 ng Recombinant Human Tau Protein (Full Length), GSK3beta-phosphorylated (line B) using Phospho-Tau (Thr217) Rabbit Monoclonal Antibody at 1:5000 dilution. |
| Application | WB |
| Recommended Dose | WB: 1:1000-1:5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around Thr217 of Human Phospho-Tau. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to the residues around Thr217 of Human Phospho-Tau |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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