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H-D-Phe-Pip-Arg-pNA acetate

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Catalog No. T38542Cas No. 115388-96-0
Alias S-2238 acetate, H-D-Phe-Pip-Arg-pNA acetate

H-D-Phe-Pip-Arg-pNA (S-2238) acetate is a chromogenic substrate based on the N-terminal fragment of the A alpha chain of fibrinogen, the physiological target of thrombin. As a specific indicator of thrombin activity, it is utilized to quantify thrombin. This assay ensures high sensitivity, accuracy, and ease of execution.

H-D-Phe-Pip-Arg-pNA acetate
Other Forms of H-D-Phe-Pip-Arg-pNA acetate:

H-D-Phe-Pip-Arg-pNA acetate

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Catalog No. T38542Alias S-2238 acetate, H-D-Phe-Pip-Arg-pNA acetateCas No. 115388-96-0
H-D-Phe-Pip-Arg-pNA (S-2238) acetate is a chromogenic substrate based on the N-terminal fragment of the A alpha chain of fibrinogen, the physiological target of thrombin. As a specific indicator of thrombin activity, it is utilized to quantify thrombin. This assay ensures high sensitivity, accuracy, and ease of execution.
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2 mg$1935 days5 days
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
H-D-Phe-Pip-Arg-pNA (S-2238) acetate is a chromogenic substrate based on the N-terminal fragment of the A alpha chain of fibrinogen, the physiological target of thrombin. As a specific indicator of thrombin activity, it is utilized to quantify thrombin. This assay ensures high sensitivity, accuracy, and ease of execution.
SynonymsS-2238 acetate, H-D-Phe-Pip-Arg-pNA acetate
Chemical Properties
Molecular Weight612.688
FormulaC29H40N8O7
Cas No.115388-96-0
SmilesCC(O)=O.N[C@H](Cc1ccccc1)C(=O)N1CCCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc(cc1)[N+]([O-])=O
Relative Density.no data available
SequenceH-DL-Phe-DL-Pip-DL-Arg-pNA
Sequence ShortFXR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

S-2238 AcetateS2238 AcetateS 2238 AcetateH-D-Phe-Pip-Arg-pNA AcetateHDPhePipArgpNA acetateH D Phe Pip Arg pNA acetate
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