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H-D-Phe-Pip-Arg-pNA acetate

Name: H-D-Phe-Pip-Arg-pNA acetate
Brand: TargetMol
SKU: T38542
Price: 81 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: S-2238 acetate, S2238 acetate, S 2238 acetate) Copy Product Info

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Synonyms: S-2238 acetate, S2238 acetate, S 2238 acetate

Catalog No. T38542 Copy Product Info

Purity: 98.86%

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H-D-Phe-Pip-Arg-pNA acetate is a chromogenic substrate whose sequence mimics the N-terminal region of thrombin's natural substrate fibrinogen α-chain. It is highly specific to thrombin and can be used for the activity detection of antithrombin Ⅲ heparin cofactor (AT-III). The AT-III detection method based on this chromogenic substrate features high sensitivity, accurate results and simple operation.

Cas No. 115388-96-0

Pack Size	Price	USA Stock	Global Stock
1 mg	$81	-	In Stock
5 mg	$197	-	In Stock
10 mg	$247	-	In Stock
25 mg	$418	-	In Stock
50 mg	$595	-	In Stock
100 mg	$862	-	In Stock
1 mL x 10 mM (in DMSO)	$266	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98.86%

Appearance:Solid

Color:White

Resource Download

COA LCMS

Product Introduction

Bioactivity

Description

Synonyms

S-2238 acetate, S2238 acetate, S 2238 acetate

Chemical Properties

Molecular Weight	612.69
Formula	C₂₉H₄₀N₈O₇
Cas No.	115388-96-0
Smiles	CC(O)=O.[O-][N+](C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCCC2)C([C@H](N)CC3=CC=CC=C3)=O)=O)=O)=O
Relative Density.	no data available
Sequence	H-{DL-Phe}-{DL-Pip}-{DL-Arg}-pNA
Sequence Short	FXR

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80.00 mg/mL (130.57 mM)

DMSO: 80.00 mg/mL (130.57 mM)

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6321 mL	8.1607 mL	16.3215 mL	81.6073 mL
5 mM	0.3264 mL	1.6321 mL	3.2643 mL	16.3215 mL
10 mM	0.1632 mL	0.8161 mL	1.6321 mL	8.1607 mL
20 mM	0.0816 mL	0.4080 mL	0.8161 mL	4.0804 mL
50 mM	0.0326 mL	0.1632 mL	0.3264 mL	1.6321 mL
100 mM	0.0163 mL	0.0816 mL	0.1632 mL	0.8161 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

H-D-Phe-Pip-Arg-pNA AcetateHDPhePipArgpNA acetateH D Phe Pip Arg pNA acetate

Related Tags: H-D-Phe-Pip-Arg-pNA acetate chemical structure | H-D-Phe-Pip-Arg-pNA acetate formula | H-D-Phe-Pip-Arg-pNA acetate molecular weight