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Anti-GSTP1 Antibody (5M149) is a Rabbit antibody targeting GSTP1. Anti-GSTP1 Antibody (5M149) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-GSTP1 Antibody (5M149) is a Rabbit antibody targeting GSTP1. Anti-GSTP1 Antibody (5M149) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 5M149 |
Reactivity | Human |
Verified Activity | 1. Anti-GSTP1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Jurkat Whole Cell Lysate. -Lane B: K562 Whole Cell Lysate. -Lane C: Molt-4 Whole Cell Lysate. -Lane D: HeLa Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:23 kDa. 2. Anti-GSTP1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell Lysate. -Lane B: GSTP1 konckout Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:23 kDa. |
Application | WB |
Recommended Dose | WB: 1:500-1:2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the Human GSTP1. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Glutathione S-transferase (GST) family members promote carcinogenesis and cancer progression. GSTP1 levels correlated negatively with tumor size and serum alpha-fetoprotein (AFP) in HCC patients, and higher GSTP1 levels were associated with longer overall survival (OS) and disease-free survival (DFS), the high GSTP1 levels provide a better prognosis through suppression of tumorigenesis in HCC. Dual-testing of HPV and the GSTP1 might prove an effective screening tool for cervical cancer. GSTP1 is highly expressed in various cancerous cells and pre-neoplastic legions, where it is involved in apoptotic resistance or metabolism of several anti-tumor chemotherapeutics. That GSTP1 is a marker of malignant and pre-malignant cells and is a promising target for visualization and drug development. GSTP1 is a largely investigated tissue biomarker in several malignancies such as prostate, breast, lung, and hepatocellular carcinoma with good performances, especially for diagnostic purposes. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide corresponding to the N-terminus of the Human GSTP1 |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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