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Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody
(Synonyms: p-IkappaB- beta (Ser23), p-IkappaB- beta (S23), IkappaB- beta (p-Ser23), IkappaB- beta (p-S23)) Copy Product Info
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Synonyms: p-IkappaB- beta (Ser23), p-IkappaB- beta (S23), IkappaB- beta (p-Ser23), IkappaB- beta (p-S23)
Catalog No. TMAC-02120 Copy Product Info
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Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IkappaB- beta (Ser23). Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-IkappaB- beta
(Ser23) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $217 | 7-10 days | 7-10 days | |
| 100 µL | $316 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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| Description | Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IkappaB- beta (Ser23). Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody can be used in IHC,WB. |
| Synonyms | p-IkappaB- beta (Ser23), p-IkappaB- beta (S23), IkappaB- beta (p-Ser23), IkappaB- beta (p-S23) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-b (Phospho-Ser23) Antibody TMAC-02120 (left) or the same antibody preincubated with blocking peptide (right). 2. Western blot analysis of extracts from HT29 cells, treated with CA or calf intestinal phosphatase (CIP), using IkB-b (Phospho-Ser23) Antibody TMAC-02120.  , |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 23 (L-G-S(p)-L-G) derived from Human IkB-b |
| Antigen Species | Human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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