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Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody (Synonyms: p-IkappaB- beta (Ser23), p-IkappaB- beta (S23...)

Catalog No. TMAC-02120 Copy Product Info
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Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IkappaB- beta (Ser23). Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-02120
Synonyms p-IkappaB- beta (Ser23), p-IkappaB- beta (S23), IkappaB- beta (p-Ser23), IkappaB- beta (p-S23)

Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IkappaB- beta (Ser23). Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-IkappaB- beta
(Ser23) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IkappaB- beta (Ser23). Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody can be used in IHC,WB.
Synonymsp-IkappaB- beta (Ser23), p-IkappaB- beta (S23), IkappaB- beta (p-Ser23), IkappaB- beta (p-S23)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-b (Phospho-Ser23) Antibody TMAC-02120 (left) or the same antibody preincubated with blocking peptide (right).
2. Western blot analysis of extracts from HT29 cells, treated with CA or calf intestinal phosphatase (CIP), using IkB-b (Phospho-Ser23) Antibody TMAC-02120.
verifiedActivityverifiedActivity
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundInhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 23 (L-G-S(p)-L-G) derived from Human IkB-b
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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