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Synonyms: EC 4.6.1.1, Ca(2+)/calmodulin-activated adenylyl cyclase, Ca(2+)/calmodulin activated adenylyl cyclase, Brain adenylate cyclase 1, ATP pyrophosphate-lyase 1, ATP pyrophosphate lyase, Adenylyl cyclase 1, adenylate cyclase type I, Adenylate cyclase type 1, adenyl cyclase, ADCY1, 3'5' cyclic AMP synthetase
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-Adenylate cyclase 1 Polyclonal Antibody is a Rabbit antibody targeting Adenylate cyclase 1. Anti-Adenylate cyclase 1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | EC 4.6.1.1, Ca(2+)/calmodulin-activated adenylyl cyclase, Ca(2+)/calmodulin activated adenylyl cyclase, Brain adenylate cyclase 1, ATP pyrophosphate-lyase 1, ATP pyrophosphate lyase, Adenylyl cyclase 1, adenylate cyclase type I, Adenylate cyclase type 1, adenyl cyclase, ADCY1, 3'5' cyclic AMP synthetase |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Brain, retina and adrenal medulla. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The membrane bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein coupled receptors. Eight human AC isoforms (AC-1 through AC-4) have been identified up to now and genes for at least nine adenylate cyclase (AC-1-AC-9) have been cloned characterized and sequenced. This is a calmodulin-sensitive adenylyl cyclase which may be involved in regulatory processes in the central nervous system. It may play a role in neuronal plasticity, memory acquisition and learning and is expressed predominantly in the brain, retina and adrenal medulla. |
| Immunogen | KLH conjugated synthetic peptide: human adenylate cyclase type I |
| Antigen Species | Human |
| Gene Name | ADCY1 |
| Gene ID | |
| Protein Name | Adenylate cyclase type 1 |
| Uniprot ID | |
| Biology Area | Integration of energy metabolism,Integration of energy,Cancer,Regulation,Regulators |
| Function | This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. |
| Molecular Weight | Theoretical: 123 kDa. Actual: 123 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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