ASGR1 Protein, Human, Recombinant (His)

Name: ASGR1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-02702
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: HL-1, CLEC4H1, asialoglycoprotein receptor 1, ASGPR1, ASGPR) Copy Product Info

Synonyms: HL-1, CLEC4H1, asialoglycoprotein receptor 1, ASGPR1, ASGPR

Catalog No. TMPY-02702 Copy Product Info

Purity: 98.4%

ASGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.8 kDa and the accession number is P07306.

Pack Size	Price	USA Stock	Global Stock
5 µg	$47	-	In Stock
10 µg	$73	-	In Stock
20 µg	$117	-	In Stock
50 µg	$225	-	In Stock
100 µg	$376	-	In Stock
200 µg	$665	7-10 days	7-10 days
500 µg	$1,410	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:98.4%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	ASGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.8 kDa and the accession number is P07306.
Species	Human
Expression System	HEK293 Cells
Tag	N-His
Accession Number	P07306
Construction	Gln62-Leu291
Protein Purity	> 90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	HL-1, CLEC4H1, asialoglycoprotein receptor 1, ASGPR1, ASGPR
Research Background	The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The research regarded that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development.

Chemical Properties

Molecular Weight

28.8 kDa (predicted); 38-55 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.