Anti-PD-1 Antibody (2F89)

Name: Anti-PD-1 Antibody (2F89)
Brand: TargetMol
SKU: TMAY-03666
Rating: 4.5 (1 reviews)

😃Good

Catalog No. TMAY-03666

Alias SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (2F89) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (2F89) can be used in ELISA.

Anti-PD-1 Antibody (2F89)

😃Good

Catalog No. TMAY-03666Alias SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (2F89) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (2F89) can be used in ELISA.

Pack Size	Price	Availability	Quantity
20 μL	$94	7-10 days
100 μL	$268	7-10 days

Bulk & Custom

Add to Cart

Questions

Resource Download

Instruction Manual of Detection Antibody

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Canine
Alias	SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279
Ig Type	Rabbit IgG
Clone	2F89
Reactivity	Canine
Application	ELISA
Recommended Dose	ELISA: 1:5000-1:10000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Canine PD1 / PDCD1 / CD279 ( TMPY-04342; XP_022265285.1; Met1-Leu169).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyrosine phosphatase, SHP-2 upon interacting with either of two ligands, PD-L1 or PD-L2. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. Furthermore, PD1 is shown to be a regulator of virus-specific CD8+ T cell survival in HIV infection. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Blockade: Blocking AntibodiImmune Checkpoint Blockade: PD1 / PDCD1 / CD2Immune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyPD1 / PDCD1 / CD279 Immune CheckpointPD1 / PDCD1 / CD279 Immune Checkpoint AntibodPD1 / PDCD1 / CD279 Immune Checkpoint ProteinTargeted Therapy

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Canine PD1 / PDCD1 / CD279 Protein (TMPY-04342)
Antigen Species	Canine
Biology Area	ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

Sci Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc