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Anti-EGFR Antibody (6Z678) (Synonyms: PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor rece...)
Catalog No. TMAY-00023 Copy Product Info
🥰Excellent
Anti-EGFR Antibody (6Z678) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (6Z678) can be used in IHC-P.
Anti-EGFR Antibody (6Z678)
Copy Product Info🥰Excellent
Catalog No. TMAY-00023
Synonyms PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Anti-EGFR Antibody (6Z678) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (6Z678) can be used in IHC-P.
Anti-EGFR Antibody
(6Z678)
(6Z678)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
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| Description | Anti-EGFR Antibody (6Z678) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (6Z678) can be used in IHC-P. |
| Synonyms | PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor |
| Ig Type | Mouse IgG1 |
| Clone | 6Z678 |
| Reactivity | Human |
| Specificity | Human EGFR No cross-reactivity in ELISA with Mouse EGFR Human ERBB2 Human ERBB3 Human ERBB4 |
| Verified Activity | 1. Immunochemical staining of human EGFR in human rectal carcinoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human EGFR in human placenta with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to trophoblast. 3. Immunochemical staining of human EGFR in human esophageal carcinoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1; TMPY-04529; NP_005219; Met668-Ala1210). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human EGFR / HER1 / ErbB1 protein (TMPY-04529) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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