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TargetMol | Compound Library

Multi-Target Compound Library

Catalog No. L9510

The pathogenesis of complex diseases often involves the interplay of multiple biological targets and signaling pathways, making it difficult for single-target drugs to achieve optimal therapeutic outcomes. As a result, single-target treatment strategies may have limited efficacy in certain cases. In contrast, multi-target drugs can act on multiple key targets or related pathways simultaneously, producing synergistic effects that significantly enhance therapeutic effectiveness.
This integrated intervention approach not only facilitates more comprehensive regulation of disease-associated biological networks but also helps to reduce the risk of drug resistance caused by mutations in individual targets. Moreover, due to the synergistic interactions between different targets, multi-target drugs can achieve desired therapeutic outcomes at lower dosages, thereby reducing toxicity and improving both safety and tolerability.
Therefore, multi-target drugs offer a more systematic and efficient strategy for the treatment of complex diseases.
TargetMol’s Multi-Target Compound Library contains 5200 compounds that act on two or more distinct targets, providing a valuable resource for the development of multi-target therapeutics.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9510

Multi-Target Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 5200 types of multi-target compounds for high throughput screening (HTS) and high content screening (HCS);
  • Approved by FDA and already on the market;
  • Structurally diverse, medicin active, and cell-permeable.
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are available in stock for immediate delivery.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Endogenous Metabolite
5-HT Receptor
Antibacterial
NF-κB
CDK
PI3K
COX
Dopamine Receptor
Adrenergic Receptor
AChR
Potassium Channel
DNA/RNA Synthesis
EGFR
VEGFR
HIV Protease
Cytochromes P450
Reactive Oxygen Species
Calcium Channel
Antibiotic
Akt
ERK
Parasite
TNF
Ras
Histamine Receptor
p38 MAPK
Epigenetic Reader Domain
mTOR
Sodium Channel
PPAR
JAK
Src
Estrogen/progestogen Receptor
PDGFR
FLT
Virus Protease
Dehydrogenase
Ferroptosis
Caspase
PDE
iGluR
Bcl-2 Family
HDAC
FGFR
IL Receptor
SARS-CoV
Influenza Virus
STAT
PKC
Estrogen Receptor/ERR
NO Synthase
Histone Methyltransferase
PARP
TRP/TRPV Channel
c-Kit
Interleukin
Wnt/beta-catenin
AMPK
GABA Receptor
GSK-3
Microtubule Associated
MMP
Antifungal
c-Met/HGFR
NMDAR
Bcr-Abl
GluR
MDM-2/p53
Cholinesterase (ChE)
Prostaglandin Receptor
ALK
Raf
ROS
MAO
MAPK
Mitophagy
Monoamine Oxidase
JNK
Phosphatase
Tyrosine Kinases
HSV
Aurora Kinase
HIF/HIF Prolyl-Hydroxylase
Topoisomerase
TGF-beta/Smad
TLR
Beta Amyloid
HCV Protease
GPCR
Proteasome
HSP
MEK
Casein Kinase
PKA
Drug Metabolite
Lipoxygenase
Norepinephrine
Reverse Transcriptase
Cannabinoid Receptor
Serotonin Transporter
ATPase
E1/E2/E3 Enzyme
p53
Adenosine Receptor
Mitochondrial Metabolism
Sirtuin
IκB/IKK
ROCK
P-gp
LPL Receptor
Nrf2
S6 Kinase
IGF-1R
Antiviral
Phospholipase
NOS
RAAS
Serine Protease
Anti-infection
TAM Receptor
Glucocorticoid Receptor
DNA-PK
HBV
Gamma-secretase
Serine/threonin kinase
Retinoid Receptor
HIF
S1P Receptor
Carbonic Anhydrase
Nucleoside Antimetabolite/Analog
c-RET
HER
Antioxidant
Trk receptor
Opioid Receptor
DUB
Integrin
Androgen Receptor
Histone Acetyltransferase
Tyrosinase
NOD-like Receptor (NLR)
Cysteine Protease
c-Fms
Histone Demethylase
Progesterone Receptor
FAK
Mdm2
PERK
Pim
Transferase
DYRK
CXCR
NOD
PROTACs
DNA Alkylator/Crosslinker
Rho
CCR
CaMK
HMG-CoA Reductase
ROS Kinase
Glucosidase
Hedgehog/Smoothened
ATM/ATR
Syk
BACE
NADPH
MRP
Aryl Hydrocarbon Receptor
Beta-Secretase
DNA Methyltransferase
Sigma receptor
Kras
Glutathione Peroxidase
DPP-4
Angiotensin-converting Enzyme (ACE)
Chk
transporter
PLK
Proton pump
IDO
Immunology/Inflammation related
RIP kinase
P2X Receptor
Antifection
Smo
Fatty Acid Synthase
Indoleamine 2,3-Dioxygenase (IDO)
Chloride channel
PAK
FAAH
Acyltransferase
AhR
Reductase
c-Myc
DNA Alkylation
DNA
Leukotriene Receptor
CSF-1R
Isocitrate Dehydrogenase (IDH)
Stearoyl-CoA Desaturase (SCD)
cAMP
GPCR19
PDK
ADC Cytotoxin
LTR
FXR
LDL
ABC Transporter
SGLT
Thrombin
Kinesin
YAP
P2Y Receptor
Melatonin Receptor
Liver X Receptor
IAP
PGE Synthase
IRAK
IFNAR
Tie-2
UGT
Telomerase
MNK
Pyroptosis
LPA Receptor
DHFR
Amino Acids and Derivatives
Myosin
MT Receptor
Molecular Glues
Endothelin Receptor
PTEN
OX Receptor
Lipid
OXPHOS
LRRK2
PI4K
Discoidin Domain Receptor (DDR)
CFTR
PD-1/PD-L1
BTK
GTPase
Antifolate
PYK2
DNA gyrase
Monoamine Transporter
Xanthine Oxidase
Epoxide Hydrolase
BCRP
ribosome
Aromatase
Thyroid hormone receptor(THR)
MicroRNA
ROR
Ligands for Target Protein for PROTAC
LIM Kinase
Annexin A
Vasopressin Receptor
STING
Free radical scavengers
Aminopeptidase
Ephrin Receptor
RSV
GST
SGK
NADPH-oxidase
MLK
Arginase
Lipase
SIK
PAFR
Guanylate cyclase
PAI-1
FKBP
CRISPR/Cas9
Hydroxylase
Complement System
Neurokinin receptor
Platelet aggregation
IKZF
RAR/RXR
Arrestin
Necroptosis
Factor Xa
NAMPT
Glucokinase
Glucagon Receptor
Phosphorylase
MAGL
ATP Citrate Lyase
OAT
ASK
GPX
Protease-activated Receptor
Imidazoline Receptor
NPC1L1
Dynamin
MyD88
Na+/Ca2+ Exchanger
Bcl-6
AAK1
Glutaminase
NR4A
IRE1
MTH1
GRK
ACK1
Survivin
Porcupine
AIM2
Decarboxylase
cGAS
Carboxypeptidase
Melanin-concentrating Hormone Receptor (MCHR)
Adenylyl Cyclase
Transaminase
NEDD8
TOPK
OCT
Cholecystokinin Receptor
Hck
ATG
Amylase
GlyT
Hexokinase
Bombesin Receptor
PAD
Thrombopoietin Receptor
GluCls
CRFR
Methionine Adenosyltransferase (MAT)
Ligand for E3 Ligase
Melanocortin Receptor
GHSR
Adenosine Deaminase
CGRP Receptor
Cuproptosis
Gap Junction Protein
FOXO3
Advanced Glycation End Products
Monocarboxylate transporter
CRM1
gp120/CD4
MIF
VDA
GNRH Receptor
ASCT
Cell Cycle Arrest
LDLR
FLAP
Neuropeptide FF Receptor
Adiponectin Receptor
Haspin Kinase
AAK1 (AP2 associated kinase 1)
Arp2/3 Complex
Na-K-Cl cotransporter
KSP
Cadherin
Wee1
Huntingtin
Glutathione reductase
CPT
MELK
Neprilysin
Hippo pathway
p62
Protease
KLF
Oxytocin Receptor
Aquaporin
FOXO
REV-ERB
DAPK
BMI-1
Lysosomal Autophagy
PKM
Taste receptor
CAT
GSNOR
EBI2/GPR183
Y Box Binding Protein 1
Aconitase
Cell wall
CETP
N-Acetylglucosaminyltransferase
CaSR
Photosensitizer
RANKL/RANK
Prolyl Endopeptidase (PREP)
Fas/FasL
FABP
Anion Exchanger
Integrase
PROTAC Linker
HCN Channel
Neuropeptide Y Receptor
Somatostatin
Orphan Receptor
Urea Transporter
hCE
Acetyl-CoA Carboxylase
RXFP receptor
ATTECs
APC/C
p97

Keywords