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C12-Sphingosine

Name: C12-Sphingosine
Brand: TargetMol
SKU: T38685
Price: 125 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T38685Cas No. 128427-86-1

Alias Sphingosine (d12:1)

C12-Sphingosine (Sphingosine (d12:1)) is a sphingosine congener with 12 carbon atoms, inducing serine palmitoyltransferase activity in a time- and concentration-dependent manner.

C12-Sphingosine

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Purity: 99.93%

Catalog No. T38685Alias Sphingosine (d12:1)Cas No. 128427-86-1

C12-Sphingosine (Sphingosine (d12:1)) is a sphingosine congener with 12 carbon atoms, inducing serine palmitoyltransferase activity in a time- and concentration-dependent manner.

Pack Size	Price	Availability
500 μg	$125	In Stock
1 mg	$190	In Stock
5 mg	$463	In Stock
10 mg	$666	In Stock
25 mg	$987	In Stock
50 mg	$1,380	In Stock
100 mg	$1,860	In Stock
200 mg	$2,490	In Stock

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Purity:99.93%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	C12-Sphingosine (Sphingosine (d12:1)) is a sphingosine congener with 12 carbon atoms, inducing serine palmitoyltransferase activity in a time- and concentration-dependent manner.
In vitro	After pretreatment with C12-Sphingosine (50 μM), the Vmax values of both substrates of SPT were significantly decreased. [1]
Synonyms	Sphingosine (d12:1)

Chemical Properties

Molecular Weight	215.33
Formula	C₁₂H₂₅NO₂
Cas No.	128427-86-1
Smiles	[C@@H](/C=C/CCCCCCC)([C@H](CO)N)O
Relative Density.	0.980 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

C12-SphingosineC-12-SphingosineC12SphingosineC12 Sphingosine