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Anti-Caspase-14 Antibody (3A777)

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Catalog No. TMAC-00578
Alias caspase 14, apoptosis-related cysteine peptidase, ARCI12

Anti-Caspase-14 Antibody (3A777) is a Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody (3A777) can be used in WB,ICC/IF,IHC,IP,FCM.

Anti-Caspase-14 Antibody (3A777)

Anti-Caspase-14 Antibody (3A777)

😃Good
Catalog No. TMAC-00578Alias caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody (3A777) is a Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody (3A777) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Caspase-14 Antibody (3A777) is a Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody (3A777) can be used in WB,ICC/IF,IHC,IP,FCM.
Synonymscaspase 14, apoptosis-related cysteine peptidase, ARCI12
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Caspase-14 on MCF-7 cells lysates using anti-Caspase-14 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Caspase-14 antibody. Counter stained with hematoxylin.
3. ICC staining Caspase-14 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Caspase-14 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining Caspase-14 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of A431 cells with Caspase-14 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundA unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is composed of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, caspase-10, and caspase-14. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-14, also designated MICE (for mini-ICE), is highly expressed in embryonic tissues but appears to be absent from adult tissues. Procaspase-14 can be processed in vitro by caspase-8 and caspase-10 but not by other caspases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 28 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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