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Anti-TNF beta Antibody (4P839)
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Catalog No. TMAY-00541
Alias TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT
Anti-TNF beta Antibody (4P839) is a Mouse antibody targeting TNF beta. Anti-TNF beta Antibody (4P839) can be used in ELISA,ELISA(Cap).
Anti-TNF beta Antibody (4P839)
Anti-TNF beta Antibody (4P839)
😃Good
Catalog No. TMAY-00541Alias TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT
Anti-TNF beta Antibody (4P839) is a Mouse antibody targeting TNF beta. Anti-TNF beta Antibody (4P839) can be used in ELISA,ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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| Description | Anti-TNF beta Antibody (4P839) is a Mouse antibody targeting TNF beta. Anti-TNF beta Antibody (4P839) can be used in ELISA,ELISA(Cap). |
| Synonyms | TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT |
| Ig Type | Mouse IgG1 |
| Clone | 4P839 |
| Reactivity | Human |
| Specificity | Human Lymphotoxin alpha/TNF beta |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha (rh TNF-beta / TNFSF1 / Lymphotoxin alpha ; TMPY-02153; P01374; Leu 35-Leu 205). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
| Research Background | Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TNF-beta / TNFSF1 / Lymphotoxin alpha protein (TMPY-02153) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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