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PLA2G2A Protein, Human, Recombinant (His)

(Synonyms: sPLA2, PLAS1, PLA2S, PLA2L, PLA2B, PLA2, phospholipase A2, group IIA (platelets, synovial fluid), MOM1) Copy Product Info

Synonyms: sPLA2, PLAS1, PLA2S, PLA2L, PLA2B, PLA2, phospholipase A2, group IIA (platelets, synovial fluid), MOM1

Catalog No. TMPY-01705 Copy Product Info
PLA2G2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is A0A024RA96.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$93-In Stock
10 µg$1527-10 days7-10 days
20 µg$2487-10 days7-10 days
50 µg$5777-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
PLA2G2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is A0A024RA96.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP14555
ConstructionA DNA sequence encoding the human PLA2G2A (NP_000291.1) (Met 1-Cys 144) was expressed, with a polyhistidine tag at the C-terminus. Predicted N terminal: Asn 21
Protein Purity
> 97 % as determined by SDS-PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymssPLA2, PLAS1, PLA2S, PLA2L, PLA2B, PLA2, phospholipase A2, group IIA (platelets, synovial fluid), MOM1
Research Background
Phospholipase A2, membrane associated, also known as Phosphatidylcholine 2-acylhydrolase 2A, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2 and PLA2G2A, is a peripheral membrane protein that belongs to the phospholipase A2 family. PLA2G2A is found in many cells and also extracellularly. The membrane-bound and secreted forms of PLA2G2A are identical. PLA2G2A has been proposed to play a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway. PLA2G2A is thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. PLA2G2A catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. PLA2G2A might be a factor in human colorectal tumorigenesis.
Chemical Properties
Molecular Weight15.4 kDa (predicted); 19 kDa (reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: PLA2G2A Protein, Human, Recombinant (His) chemical structure | PLA2G2A Protein, Human, Recombinant (His) molecular weight