LRG1 Protein, Human, Recombinant

Name: LRG1 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-04018
Price: 75 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: LRG, leucine-rich α-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein 1, HMFT1766) Copy Product Info

Synonyms: LRG, leucine-rich α-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein 1, HMFT1766

Catalog No. TMPY-04018 Copy Product Info

LRG1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.1 kDa and the accession number is AAH34389.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$75	-	In Stock
10 µg	$118	-	In Stock
20 µg	$196	-	In Stock
50 µg	$386	-	In Stock
100 µg	$660	7-10 days	7-10 days
200 µg	$1,120	7-10 days	7-10 days
500 µg	$2,270	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:SDS-PAGE: 95.4%; SEC-HPLC: 97.8%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	LRG1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.1 kDa and the accession number is AAH34389.1.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	AAH34389.1
Construction	A DNA sequence encoding the human LRG1 (AAH34389.1) (Met1-Gln347) was expressed with six amino acids (LEVLFQ) at the C-terminus. Predicted N terminal: Val 36
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	LRG, leucine-rich α-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein 1, HMFT1766
Research Background	LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. It contains 4 LIM zinc-binding domains and 1 Rho-GAP domain. LRG1 is involved in promoting neovascularization (new blood vessel growth) by causing a switch in transforming growth factor-beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. It may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Diseases associated with LRG1 include Appendicitis and Normal Pressure Hydrocephalus.

Chemical Properties

Molecular Weight

35.1 kDa (predicted); 45 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.