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CCL8 Protein, Human, Recombinant

Catalog No. TMPJ-00010
Synonyms: Monocyte Chemoattractant Protein 2, C-C Motif Chemokine 8, MCP2, Monocyte Chemotactic Protein 2, MCP-2, SCYA10, HC14, SCYA8, Small-Inducible Cytokine A8, CCL8

Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CCL8 Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.
Species Human
Expression System E. coli
Tag None
Accession Number P80075
Synonyms Monocyte Chemoattractant Protein 2, C-C Motif Chemokine 8, MCP2, Monocyte Chemotactic Protein 2, MCP-2, SCYA10, HC14, SCYA8, Small-Inducible Cytokine A8, CCL8
Amino Acid Gln24-Pro99
Construction Recombinant Human C-C Motif Chemokine 8 is produced by our E.coli expression system and the target gene encoding Gln24-Pro99 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 12 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.

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Keywords

CCL8 Protein, Human, Recombinant Monocyte Chemoattractant Protein 2 CCL 8 SCYA 8 C-C Motif Chemokine 8 SCYA-10 HC-14 CCL-8 MCP2 Monocyte Chemotactic Protein 2 HC 14 MCP-2 SCYA10 MCP 2 HC14 SCYA-8 SCYA8 Small-Inducible Cytokine A8 CCL8 SCYA 10 recombinant recombinant-proteins proteins protein

 

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