MCP-2/CCL8 Protein, Human, Recombinant

Name: MCP-2/CCL8 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-00010
Rating: 4.5 (1 reviews)

(Synonyms: Small-Inducible Cytokine A8, SCYA8, SCYA10, Monocyte Chemotactic Protein 2, Monocyte Chemoattractant Protein 2, MCP-2, MCP2, HC14, CCL8, C-C Motif Chemokine 8) Copy Product Info

Synonyms: Small-Inducible Cytokine A8, SCYA8, SCYA10, Monocyte Chemotactic Protein 2, Monocyte Chemoattractant Protein 2, MCP-2, MCP2, HC14, CCL8, C-C Motif Chemokine 8

Catalog No. TMPJ-00010 Copy Product Info

CCL8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12 KDa and the accession number is P80075.

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	7-10 days	7-10 days
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CCL8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12 KDa and the accession number is P80075.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P80075
Amino Acid	Gln24-Pro99
Construction	Gln24-Pro99
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Small-Inducible Cytokine A8, SCYA8, SCYA10, Monocyte Chemotactic Protein 2, Monocyte Chemoattractant Protein 2, MCP-2, MCP2, HC14, CCL8, C-C Motif Chemokine 8
Research Background	Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.

Chemical Properties

Molecular Weight

12 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.