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Anti-Phospho-PTP1B (Ser50) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTP1B (Ser50). Anti-Phospho-PTP1B (Ser50) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-PTP1B (Ser50) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTP1B (Ser50). Anti-Phospho-PTP1B (Ser50) Polyclonal Antibody can be used in WB. |
| Synonyms | PTP1B (p-Ser50), PTP1B (p-S50), p-PTP1B (Ser50), p-PTP1B (S50) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat,Monkey |
| Verified Activity | 1. Western blot analysis of extracts from COS-7 cells untreated or treated with UV using PTP1B (Phospho-Ser50) Antibody TMAC-03464. ![]() |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 50(D-V-S(p)-P-F) derived from Human PTP1B |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 49 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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