SARS-COV-2 Spike S Trimer Protein (His & Avi)

Name: SARS-COV-2 Spike S Trimer Protein (His & Avi)
Brand: TargetMol
SKU: TMPK-00438
Price: 68 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Spike glycoprotein, S protein, S glycoprotein, COVID-19) Copy Product Info

Synonyms: Spike glycoprotein, S protein, S glycoprotein, COVID-19

Catalog No. TMPK-00438 Copy Product Info

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the accession number is A0A6G7K2L4.

SARS-COV-2 Spike S Trimer Protein (His & Avi)

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	-	In Stock
10 µg	$108	-	In Stock
20 µg	$177	-	In Stock
50 µg	$346	7-10 days	7-10 days
100 µg	$581	-	In Stock
200 µg	$1,050	7-10 days	7-10 days
500 µg	$2,330	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Bis-Tris PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized SARS-COV-2 Spike S Trimer, His Tag at 1μg/ml (100μl/Well). Dose response curve for Human ACE2, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA.
Description	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the accession number is A0A6G7K2L4.
Species	SARS-CoV-2
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	A0A6G7K2L4
Construction	Val16-Glu1188
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Spike glycoprotein, S protein, S glycoprotein, COVID-19
Research Background	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Chemical Properties

Molecular Weight

136.6 kDa (predicted). Due to glycosylation, the protein migrates to 175-230 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.