PAI-1 Protein, Mouse, Recombinant (His)

Name: PAI-1 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPH-02833
Price: 123 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Serpine1, Serpin E1, Plasminogen activator inhibitor 1, Planh1, PAI-1, Pai1, PAI, Mr1, Endothelial plasminogen activator inhibitor) Copy Product Info

Synonyms: Serpine1, Serpin E1, Plasminogen activator inhibitor 1, Planh1, PAI-1, Pai1, PAI, Mr1, Endothelial plasminogen activator inhibitor

Catalog No. TMPH-02833 Copy Product Info

PAI-1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 44.9 kDa and the accession number is P22777.

Pack Size	Price	USA Stock	Global Stock
5 µg	$123	-	In Stock
10 µg	$198	-	In Stock
20 µg	$339	-	In Stock
50 µg	$497	20 days	20 days
100 µg	$696	20 days	20 days
200 µg	$1,070	20 days	20 days
500 µg	$1,890	20 days	20 days
1 mg	$2,970	20 days	20 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:90%

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	PAI-1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 44.9 kDa and the accession number is P22777.
Species	Mouse
Expression System	P. pastoris (Yeast)
Tag	N-6xHis
Accession Number	P22777
Amino Acid	TLPLRESHTAHQATDFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNEKGTAHALRQLSKELMGPWNKNEISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVDFSEVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQRDTLSMFIAAPFEKDVHLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFSATLADFTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVIDRSFLFVVRHNPTETILFMGQVMEP
Construction	23-402 aa
Protein Purity	> 90% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 0.5M NaCl, 6% Trehalose, pH8.0.
Reconstitution	Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%.
Synonyms	Serpine1, Serpin E1, Plasminogen activator inhibitor 1, Planh1, PAI-1, Pai1, PAI, Mr1, Endothelial plasminogen activator inhibitor
Research Background	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. Involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.

Chemical Properties

Molecular Weight

44.9 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.