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Pralidoxime Chloride

🥰Excellent
Catalog No. T1111Cas No. 51-15-0
Alias 2-Pyridinealdoxime methochloride, 2-PAM chloride, 2-PAM (chloride)

Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates or acetylcholinesterase inhibitors (nerve agents).

Pralidoxime Chloride
Other Forms of Pralidoxime Chloride:

Pralidoxime Chloride

🥰Excellent
Purity: 99.84%
Catalog No. T1111Alias 2-Pyridinealdoxime methochloride, 2-PAM chloride, 2-PAM (chloride)Cas No. 51-15-0
Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates or acetylcholinesterase inhibitors (nerve agents).
Pack SizePriceAvailabilityQuantity
100 mg$30In Stock
500 mg$65In Stock
1 g$95In Stock
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Purity:99.84%
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Product Introduction

Bioactivity
Description
Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates or acetylcholinesterase inhibitors (nerve agents).
In vitro
The application of pralidoxime allowed the regeneration of an important fraction of inhibited AChE, process which is concentration-dependent[1].
Synonyms2-Pyridinealdoxime methochloride, 2-PAM chloride, 2-PAM (chloride)
Chemical Properties
Molecular Weight172.61
FormulaC7H9ClN2O
Cas No.51-15-0
SmilesC[n+]1ccccc1/C=N/O.[Cl-]
Relative Density.1.3265 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (289.67 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.7934 mL28.9670 mL57.9341 mL289.6704 mL
5 mM1.1587 mL5.7934 mL11.5868 mL57.9341 mL
10 mM0.5793 mL2.8967 mL5.7934 mL28.9670 mL
20 mM0.2897 mL1.4484 mL2.8967 mL14.4835 mL
50 mM0.1159 mL0.5793 mL1.1587 mL5.7934 mL
100 mM0.0579 mL0.2897 mL0.5793 mL2.8967 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

reactivatorPralidoxime ChloridePralidoximeplethymosgraphyorganophosphorusorganophosphatesnerve agentInhibitorinhibitdiethylparaoxonCholinesterase (ChE)AchE2-PAM Chloride2-PAM
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