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Glucocorticoid receptor agonist-3 Ala-Ala-Mal

Name: Glucocorticoid receptor agonist-3 Ala-Ala-Mal
Brand: TargetMol
SKU: T87849
Price: 355 USD
Availability: InStock
Rating: 5 (10 reviews)

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Glucocorticoid receptor agonist-3 Ala-Ala-Mal (Compound Preparation 8) is a conjugate of an anti-human TNFα antibody and a glucocorticoid receptor agonist (GC). Glucocorticoid receptor agonist-3 Ala-Ala-Mal (Compound Preparation 8) is utilized in research models of autoimmune and inflammatory disease biology, particularly for evaluating cytokine signaling modulation, receptor-mediated immune pathway regulation, and antibody-conjugate mechanistic profiling.

Cas No. 3014393-35-9

Pack Size	Price	USA Stock	Global Stock
1 mg	$355	-	In Stock
5 mg	$888	-	In Stock
10 mg	$1,420	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	910.98
Formula	C₄₉H₅₅FN₄O₁₂
Cas No.	3014393-35-9
Smiles	C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@@H](O2)C4=C(F)C(OCC5=CC(NC([C@@H](NC([C@@H](NC(CCN6C(=O)C=CC6=O)=O)C)=O)C)=O)=CC=C5)=CC=C4C)[H])([C@]7([C@]([C@@H](O)C3)([C@]8(C)C(CC7)=CC(=O)C=C8)[H])[H])[H]

Storage & Solubility Information

Storage

Keep away from moisture,Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (87.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0977 mL	5.4886 mL	10.9772 mL	54.8859 mL
5 mM	0.2195 mL	1.0977 mL	2.1954 mL	10.9772 mL
10 mM	0.1098 mL	0.5489 mL	1.0977 mL	5.4886 mL
20 mM	0.0549 mL	0.2744 mL	0.5489 mL	2.7443 mL
50 mM	0.0220 mL	0.1098 mL	0.2195 mL	1.0977 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DrugLinkerConjugatesforADCDrugLinker Conjugates for ADC

Related Tags: Glucocorticoid receptor agonist-3 Ala-Ala-Mal chemical structure | Glucocorticoid receptor agonist-3 Ala-Ala-Mal formula | Glucocorticoid receptor agonist-3 Ala-Ala-Mal molecular weight