IL-11 Protein, Human, Recombinant

Name: IL-11 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-03488
Price: 106 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: interleukin 11, IL-11, AGIF) Copy Product Info

Synonyms: interleukin 11, IL-11, AGIF

Catalog No. TMPY-03488 Copy Product Info

IL-11 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.1 kDa and the accession number is AAH12506.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$106	In Stock	In Stock
10 µg	$148	7-10 days	7-10 days
20 µg	$206	7-10 days	7-10 days
50 µg	$320	7-10 days	7-10 days
100 µg	$447	7-10 days	7-10 days
200 µg	$791	7-10 days	7-10 days
500 µg	$1,670	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:93.2%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1.Measured in a cell proliferation assay using T1165 mouse plasmacytoma cells. The ED50 for this effect is typically 1-8 ng/mL. 2.Loaded Human IL11RA Protein, His Tag on His1K Biosensor, can bind Human IL11 protein with an affinity constant of 0.353nM as determined in BLI assay (Routinely tested).
Description	IL-11 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.1 kDa and the accession number is AAH12506.1.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	AAH12506.1
Construction	A DNA sequence encoding the mature form of human IL11 (AAH12506.1) (Pro22-Leu199) was expressed. Predicted N terminal: Pro 22
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.1 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	interleukin 11, IL-11, AGIF
Research Background	IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation, and could be used as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

Chemical Properties

Molecular Weight

19.1 kDa (predicted); 23 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.