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Syntenin Protein, Human, Recombinant (His)

Catalog No. TMPY-04817
Synonyms: MDA-9, SYCL, TACIP18, syndecan binding protein (syntenin), ST1, MDA9

Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.

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Syntenin Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
Description Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.
Species Human
Expression System E. coli
Tag His
Accession Number O00560-1
Synonyms MDA-9, SYCL, TACIP18, syndecan binding protein (syntenin), ST1, MDA9
Construction A DNA sequence encoding the human SDCBP (NP_001007068.1) (Met1-Val298) was expressed with a polyhistidine tag at the N-terminus.
Protein Purity > 90 % as determined by SDS-PAGE.
Molecular Weight Approxiamtely 34.7 kDa
Endotoxin Please contact us for more information.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.

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Keywords

Syntenin Protein, Human, Recombinant (His) MDA-9 SYCL ST 1 syndecan binding protein TACIP18 syndecan binding protein (syntenin) MDA 9 ST1 ST-1 TACIP 18 syntenin MDA9 TACIP-18 recombinant recombinant-proteins proteins protein

 

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